Since SSRI raise serotonin levels almost immediately , why isnt there an immediate effect if depressed people lack serotonin ?

Question

Since SSRI raise serotonin levels almost immediately , why isnt there an immediate effect if depressed people lack serotonin ?

In: 57

Answer 1

SSRI clinically significant effects aren’t due to increasing serotonin, they’re due to epigenetic changes in our DNA in response to increased serotonin. Precisely how this works isn’t well understood.