There’s some good discussion here:
https://math.stackexchange.com/questions/20578/why-is-integration-so-much-harder-than-differentiation
One main answer is that differentiation is local while integration is more global.
Also, this isn’t what you’re asking but funnily enough, it’s much more likely for a function to be integrable than differentiable (in some sense). “Most” functions are integrable but “most” functions aren’t differentiable.
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