Variances have a lot of useful properties, re: distributions and random variables that are easy to calculate. For some of these measurements, the mean absolute difference might have similar properties, but usually variance is cleaner and have more fundamental properties.
For example, for independent random variables X and Y:
Mean(X+Y)=Mean(X)+Mean(Y)
Mean(X-Y)=Mean(X)-Mean(Y)
Var(X+Y)=Var(X)+Var(Y)
Var(X-Y)=Var(X)+Var(Y)
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