When you get old enough for this to be a reassuring rather than concerning explanation for a death, the person in question usually has a medical history that explains pretty well what the exact cause is. They often have a pretty good idea for months or years what’s going to give out on them. It’s normally some time of heart failure or respiratory depression, either because those organs or warn out or they’ve been damaged by things like kidney disease, blood pressure, or blood vessel disease.
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