Headaches are not actually from the brain itself. The brain is the only organ not to feel pain. (Odd I know). The pain you feel is a synapse pulse signal possibly around your temple head.
Painkillers work to block the synapse pulse or lower it which reduces or eliminates pain.
Pain is mental and can often be distracted. And it’s best to hydrate as cells tend to shrink when dehydrated. Which can cause discomfort.
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