What are hormones and how do they work?

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What are hormones and how do they work?

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A hormone is a chemical messenger, some are made from protein and others are made from fats in the body- this changes how they get around the body since protein hormones need other proteins to get around the blood, whereas fat proteins can get around on their own usually. The hormone fits like a lock and key (on a receptor) on the target tissue, so for example: specific cells in the pancreas release insulin, insulin is a peptide (protein) hormone that eventually gets to tissues (like liver and skeletal muscle) where it interacts with receptors and causes the tissue to have its effect!

The tricky thing is that there is something called positive and negative feedback. Most hormones use negative feedback to turn off those hormones so they aren’t made as often or in the same amounts. This happens with steroids for example: Steroids to build muscle introduce testosterone, a steroid hormone that is regulated by negative feedback. When the body senses a high amount of testosterone suddenly it thinks “oh we have plenty of this, we don’t need to make it anymore” and so when you stop taking steroids, it takes a little while for testosterone to be made in the proper amounts again

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