They’re often extracts, oils, and concentrates taken from real ingredients.
They’re considered to be zero calories because they’re used in such small quantities that you aren’t getting any meaningful sort of energy from them. Food labelling rules (at least in the US) allows you to round the calories per serving down so even if the one drop of flavoring added to a bottle of water adds a calorie or two, it can still legally be labelled as having zero calories.
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