What causes muscles to gradually lose their ability to function during repetitive lifting exercise?

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When doing bicep curls, the first rep is relatively easy but eventually it becomes impossible to do a single curl.

After a rest, the muscle resets and can once again lift.

What is causing the muscle exhaustion and what is it that “resets” within the muscle?

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9 Answers

Anonymous 0 Comments

There is some interesting science that points to a combination of mental and physical endurance. The idea is called Central Governor Model and it is the hypothesis is that there is a mechanism that prevents the body from “exercising” itself to death. From my understanding it is a feedback loop between the muscles and brain. Researchers aren’t sure if the fatigue signal comes from the brain or the muscles.

You can listen to a podcast about this topic as it relates to the world record for pull ups in 24 hours. [https://www.outsideonline.com/podcast/pull-artists/](https://www.outsideonline.com/podcast/pull-artists/)

You can read about it as it relates to runners here: https://thereader.mitpress.mit.edu/running-and-the-science-of-mental-toughness/

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