What chemical reaction do drugs have (in particular MDMA) that makes us more sociable and why can’t people just “be like that” when they’re sober?

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Does it remove that anxious social barrier or it something else? Really intrigued as to what goes on in the mind.

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Anonymous 0 Comments

The serotonin in our brain makes us feel pleasure, so all drugs that have a euphoric effect increase the level of serotonin in the brain. MDMA will give you a happiness feeling, but once the drug leaves your system, you have no way to create your own happiness. So you want to take more drugs, and then you can get “stuck” in a cycle of not being happy without drugs. It causes an extreme release of dopamine/serotonin in the prefrontal cortex, which causes the increase in social skills. The problem is the lack of regulation. Basically if you just do what you feel with the serotonin/dopamine release then you are probably going to burn out all those receptors, making it much harder to produce those feel-good chemicals normally. It also affects learning too, and long term memories, so that’s also not good. When you don’t have those chemicals you will most likely have a hard time regulating your mood, sleep, etc, which will cause anxiety/depression/etc.

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