“Damage” needs to be strictly defined in order to conclusively answer this. If we don’t do this, we can end up with a pretty minor amount of damage tearing the jugular artery, but hey, it’s lethal anyway.
Eventually. With a physical material, you will have the nature of force you exert on it, and the material’s resistance to various types of forces. There’s shear force, tension, compression, friction, etc. A material that chips easily can be very resistant to tension or compression stress, while easily bendable material can be very susceptible to cutting force. Once you’ve decided with the type of force you’re applying and the material you’re destroying, you’ll be able to establish how much you will need to exert to produce the desired damage.
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