They know how all medicines work, how much you can take, etc. If a medical provider sends meds that are dangerous in combination, they’ll call and work it out with the provider. If a medical provider is sending an insane amount of opioids or benzos, they can call and question the provider and even refuse to fill it. They are legally responsible for making sure the medicine is safe and correct.
There are also “compound pharmacies” these are pharmacies where they literally make the medicine in the pharmacy. It’s quite fascinating. So obviously the pharmacist is the primary person for those processes.
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