What do surrogate MRIs results mean in the context of MS?

Question

I’ve been reading that in patients with MS, surrogate MRIs are used to determine therapy or disease progress, but what does that mean? Are they simply comparing MRI hyperintensities of people with more severe MS and extrapolating that onto other individuals with more recent MS diagnoses?

In: 3

Answer 1

Checking clinical progression in MS is subjective and there are studies that propose to use MRI lesions progression as a surrogate indicator, either in clinical drug studies or clinical practice.