Ok, firstly humans have 23 couples of chromosomes, 22 “normal ones” + 1 sexual ones (XY for males and XX for females).
Normally the DNA is partially open, so that the cell can read the information in it and use it to build proteins.
When the cell undergoes mitosis, asexual reproduction, the DNA is doubled and then extremely compressed in chromosomes, so that it’s easier to move it in both daughter-cells.
The numbers of chromosomes doesn’t seem to follow any rule and more chromosomes don’t equate to more complex organisms, but a variation in the number in humans leads to problems such as the down syndrome.
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