What is a haplogroup, cause i see it alot on 23andme things
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A large group of genetic characteristics inherited from an ancient group. These generally correlate X and Y (if you have each), so you’ll have a maternal haplogroup and a paternal haplogroup. This’ll be the last major divergence your DNA came from, pointing where your ancestors came from 1000’s of years ago.
A large group of genetic characteristics inherited from an ancient group. These generally correlate X and Y (if you have each), so you’ll have a maternal haplogroup and a paternal haplogroup. This’ll be the last major divergence your DNA came from, pointing where your ancestors came from 1000’s of years ago.
A large group of genetic characteristics inherited from an ancient group. These generally correlate X and Y (if you have each), so you’ll have a maternal haplogroup and a paternal haplogroup. This’ll be the last major divergence your DNA came from, pointing where your ancestors came from 1000’s of years ago.
**At a DNA level you have alleles:**
An allele is the basepair at one loci.
Person A may have Chr1:Pos100 = AA
Person B may have Chr1:Pos100 = AA
Person C may have Chr1:Pos100 = AG
–
Person A and Person B share the same alleles at that basepair. Person C only shares one allele with the others.
–
___
–
**At a higher level, you have a haplotype:**
A haplotype is the alleles across multiple loci.
Person A may have Chr1:Pos100-101 = AA TT
Person B may have Chr1:Pos100-101 = AA GG
Person C may have Chr1:Pos100-101 = AG GG
–
Now Person A is the odd man out. Person B and Person C share the same haplotype on one of Peraon C’s chromosomes.
–
___
–
**Go up to an even higher level, you have haplogroups:**
Mitochondrial DNA (mtDNA) comes only from the mother.
Person A has mtDNA = ATAT
Person B has mtDNA = TTTA
Person C has mtDNA = ATAT
–
Now Person B is the one left out, because Person A and Person C share the same maternal lineage.
–
___
–
**So although A=B at some allele, and B=C at some haplotype, A and C share the same haplogroup.**
–
___
**At a DNA level you have alleles:**
An allele is the basepair at one loci.
Person A may have Chr1:Pos100 = AA
Person B may have Chr1:Pos100 = AA
Person C may have Chr1:Pos100 = AG
–
Person A and Person B share the same alleles at that basepair. Person C only shares one allele with the others.
–
___
–
**At a higher level, you have a haplotype:**
A haplotype is the alleles across multiple loci.
Person A may have Chr1:Pos100-101 = AA TT
Person B may have Chr1:Pos100-101 = AA GG
Person C may have Chr1:Pos100-101 = AG GG
–
Now Person A is the odd man out. Person B and Person C share the same haplotype on one of Peraon C’s chromosomes.
–
___
–
**Go up to an even higher level, you have haplogroups:**
Mitochondrial DNA (mtDNA) comes only from the mother.
Person A has mtDNA = ATAT
Person B has mtDNA = TTTA
Person C has mtDNA = ATAT
–
Now Person B is the one left out, because Person A and Person C share the same maternal lineage.
–
___
–
**So although A=B at some allele, and B=C at some haplotype, A and C share the same haplogroup.**
–
___
**At a DNA level you have alleles:**
An allele is the basepair at one loci.
Person A may have Chr1:Pos100 = AA
Person B may have Chr1:Pos100 = AA
Person C may have Chr1:Pos100 = AG
–
Person A and Person B share the same alleles at that basepair. Person C only shares one allele with the others.
–
___
–
**At a higher level, you have a haplotype:**
A haplotype is the alleles across multiple loci.
Person A may have Chr1:Pos100-101 = AA TT
Person B may have Chr1:Pos100-101 = AA GG
Person C may have Chr1:Pos100-101 = AG GG
–
Now Person A is the odd man out. Person B and Person C share the same haplotype on one of Peraon C’s chromosomes.
–
___
–
**Go up to an even higher level, you have haplogroups:**
Mitochondrial DNA (mtDNA) comes only from the mother.
Person A has mtDNA = ATAT
Person B has mtDNA = TTTA
Person C has mtDNA = ATAT
–
Now Person B is the one left out, because Person A and Person C share the same maternal lineage.
–
___
–
**So although A=B at some allele, and B=C at some haplotype, A and C share the same haplogroup.**
–
___
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