What is a haplogroup, cause i see it alot on 23andme things
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**At a DNA level you have alleles:**
An allele is the basepair at one loci.
Person A may have Chr1:Pos100 = AA
Person B may have Chr1:Pos100 = AA
Person C may have Chr1:Pos100 = AG
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Person A and Person B share the same alleles at that basepair. Person C only shares one allele with the others.
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**At a higher level, you have a haplotype:**
A haplotype is the alleles across multiple loci.
Person A may have Chr1:Pos100-101 = AA TT
Person B may have Chr1:Pos100-101 = AA GG
Person C may have Chr1:Pos100-101 = AG GG
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Now Person A is the odd man out. Person B and Person C share the same haplotype on one of Peraon C’s chromosomes.
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**Go up to an even higher level, you have haplogroups:**
Mitochondrial DNA (mtDNA) comes only from the mother.
Person A has mtDNA = ATAT
Person B has mtDNA = TTTA
Person C has mtDNA = ATAT
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Now Person B is the one left out, because Person A and Person C share the same maternal lineage.
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**So although A=B at some allele, and B=C at some haplotype, A and C share the same haplogroup.**
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