*Background*:
I had genetic testing done as I have very unusual, extreme side effects on most medications.
As it turns out, in addition to a few other differences, I am classified as a “Poor CYP2D6 Metabolizer”
For those who are versed in pharmacology or genetics:
**CYP2D6**
*4/*41
CYP2D6*4 allele enzyme activity: None
CYP2D6*41 allele enzyme activity: Reduced
This genotype is most consistent with the **poor metabolizer phenotype**. This patient may have reduced enzyme activity as compared to individuals with the normal phenotype.
None of my providers have been overly helpful in explaining what this means exactly in terms of physiology and medication. I have tried learning about it through online lectures but I am not overly versed in chemistry.
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