Basically it just means having a brain that is physically different from the “normal” human brain.
The reason there is variation there is because not everyone agrees just how narrow to define normal in the case of a human brain. Generally speaking, in modern science we prefer to define normal in a broad enough sense that anyone capable of leading a fairly normal life without major accommodation can be considered normal.
Simply put, you will not get a single simple answer because there is no agreement on what that answer would be.
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