Aside from historical reasons – some people get lasting effects, https://en.m.wikipedia.org/wiki/Hallucinogen_persisting_perception_disorder , and they are really nasty. It’s basically disability for unpredictable period from months to years.
Also, they are hard to control. Drivers, pilots, machinists and other people at high-risk professions usually pass a quick medical checkup before every shift. It takes a simple breathalizer to check for alcohol intoxication, but it’s way more complex to check for all kinds of other drugs.
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