Ok, starting again as I was way off base! Did some reading and I get it now.
Tobacco leaves contain naturally occurring nicotine as a pesticide. The amount ingested by smoking or swallowing a small amount from a nicotine pouch may make you sick or nauseous, but won’t harm you. But swallowing tobacco leaves means you’re ingesting a much larger dose of nicotine, which is poisonous* Hence the vomiting and risk of death.
**everything is poisonous in the right quantity*
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