What makes heart disease hereditary? What genes are being passed on that make you more susceptible to it?


To elaborate. What physical attribute are these genes passing on that make you more likely to have a heart attack for example?

In: 9

Off the top of my head…

Heart attacks result from a failure of blood flow to cardiac tissue. There are two main causes for this; blockages and breaches. Blockages result from a buildup of cholesterol and other materials in blood vessels, which when dislodged can get stuck and prevent blood flow to the heart. Aneurysms result when an artery tears, bleeding into intercellular space and resulting in a loss of flow downstream.

There are other forms of heart disease, that relate to blockages and breaches to blood supply elsewhere in the body, and these have similar causes.

As such, any genes that affect the elasticity of blood vessels, any genes that regulate how the body uses cholesterol, any genes that regulate the growth of new capillaries around areas of restricted flow, any genes that regulate the efficiency of the lymphatic system (which is important for swelling and pressure in extremities), any genes that affect the strength of the heart muscle itself… there’s a lot of little things that can increase or decrease risk of heart disease.

Heart disease can be hereditary because some genes that are responsible for regulating important processes in the body, such as blood pressure and cholesterol levels, can be passed down from parents to their children. These genes can affect a person’s risk of developing heart disease by making them more susceptible to certain risk factors.
For example, if a person inherits genes that cause high blood pressure or high cholesterol, they may be more likely to develop heart disease. Similarly, genes that are involved in inflammation or the formation of blood clots can also increase a person’s risk of heart disease.
It’s important to note that while genetics can play a role in heart disease, lifestyle factors such as diet, exercise, smoking, and stress also have a significant impact on a person’s risk. So, even if a person has a family history of heart disease, they can still take steps to reduce their risk by adopting healthy habits. So, basically don’t even trip homie.