When editing DNA, how does an organism know to replicate the edited DNA vs. the non-edited DNA?

Question

When editing DNA, how does an organism know to replicate the edited DNA vs. the non-edited DNA?

In: Biology

Answer 1

Every gene is under some sort of control, which is done by a sequence usually preceding the gene in question. That’s where all sorts of stuff, proteins in particular, can bind and activate the gene. So, if you edit an existing gene, it still has its old control sequences. If you insert a new gene, you have to add control sequences for it. What you use for that strongly depends on the application.