They had been sending sounding rockets, probes, and experiments into space since basically the end of WW2. The German V-2 actually left the major part of the atmosphere when bombing England.
Finally, they actually used modified weather balloons to send Joseph Kittinger to the edge of space to test a spacesuit. He held the record for highest free fall skydive until Felix Baumgartner broke it with Red Bulls help.
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