Here are several options, but there are many more
Cancer might destroy the immune system so they die of infection. This happened a lot in early days of HIV, which is literally an “immunodeficiency” virus.
Cancer might invade the brain and disrupt various body control mechanisms, or create blockages in blood and spinal fluid flow that create a sudden increase in pressure in the cranial cavity and crushes parts of the brain.
Cancer could block major arteries and airways so they suffocate.
Cancer can destroy the body’s metabolism, so they basically lose their appetite and lose weight so it’s like they are starving to death.
Cancer can cause severe internal bleeding.
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