Why are IV analgesics not harmful when used for surgery?


Why the huge difference between a single small dose vs. what we typically know as dependency inducing? Is there even a slight risk of dependency after surgery? (Assuming the analgesic is only used during surgery, and not taken afterwards for postoperative pain)

Note: Harmful is not the word I was looking for, but I had to reword my post several times to stop it from being deleted

In: 63

They are. That is why anaesthetists have a specialist training program after medical school.

You are closely monitored with all sorts of machines that go ping, have machines that can breath for you if you stop, and medication that can reverse drug effects rapidly on hand.

Would really not recommend surgical anaesthesia be given by a rando. You’ll die.

ETA addiction and tolerance are generally physiological issues related to upregulated metabolism or reduced receptors or similar. This takes time and reverts to normal if exposure is withdrawn, so single doses won’t result in physiological dependence.

The other part of addiction is psychological craving. A single dose could give an intense high that a person desires strongly so will chase more. If you’re asleep when exposed, this probably won’t be a thing.

It takes more than one dose and more than a few weeks of using opiates as prescribed to develop a physical dependence that would result in withdrawal if stopped.

r u thinking about something like ketamine/special k? its the only drug I can think of that is a well known street and anasthetic drug

In medicine, we have what’s known as the Benefit-Risk Ratio. There is not a single substance out there, even a beef hotdog, that does not have a risk or potential danger. You could choke and die from it; this has happened before and will happen in the future.

Highly Trained Physicians are paid to judge this ratio and manage the potential risks. For most procedures, the Benefit-Risk Ratio (BRP) is usually great.

#Can opioids in surgery be harmful to you? Absolutely. However, the benefit is deemed higher than the risk

I assume you mean opioids? “Harmfull” is not a good term, opioid don’t do any harm at correct dosages. That’s why they are absolutely ubiquitous in medicine and considered an essential medication to have. They are even less harmful than OTC medication like acetaminophen which is rougher on the liver. They require careful control of dose, but at that dose they are very safe and not damaging whatsoever.

If you also just mean “potential for tolerance, dependence, and addiction”, all that has to do with extended use over time and only addiction itself is technically harmful. There is basically no chance for you to.build any of those from a single event, whatever the dose. Opioids can’t magically force addiction on you, and dependence needs time to physiologically happen.

There are also weird beliefs about specifically fentanyl due to the issues with street drugs, where people act like it is a scary poison or something, but I won’t assume you meant that.

If you meant some other analgesic or some other definition of harm though let me know.