Because 99% or thereabouts of any pill is filler material. Think about it 50 mg is an amount that would be like 1/100th of a teaspoon. Or something like 100 grains of table salt. If they made a pill the size of 100 grains of salt, it could not be easily handled without precision tools – which would be useless as pills to take home. Just breathing on it would probably cause it to scatter like dust.
Basically enough filler is added so that the pill becomes large enough to be easily bonded into a pill, counted, handled and dispensed for normal people with average dexterity without using tools.
It isn’t difficult to mix together several vitamins (since vitamin daily doses are generally very small – some are measured in micrograms) and that mixture would likely still require fillers to make up a reasonably sized pill.
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