The bigger problem is transmitting the power. A power line from the middle of Siberia to anywhere with a population that needs that much electricity would be hugely expensive to build, need a bunch of its own maintenance, and would lose a significant % of the power along the way.
Since nuclear generation is very safe to begin with, it’s not worth paying more and also getting less power just to put it way out of the way.
In fact the next generation of nuclear generation is likely going to be SMRs (Small Modular Reactors) – bigger number of smaller reactors that are even less centralized and even closer to where the customers live.
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