Why are so many drugs “[blank] hydrochloride”?

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I noticed that cocaine and ecstacy are referred to as cocaine hydrochloride and MDMA hydrochloride. I have allergy medication in my cabinet that is diphenhydramine hydrochloride.

What’s a hydrochloride and why is it part of a lot of drugs?

In: Chemistry

7 Answers

Anonymous 0 Comments

It’s the salt form of the drug. Reacting an organic base (like many drugs) with an acid creates the salt form of that drug. A lot of drugs are sold in a salt form because it makes them water soluble and increases their absorption in your stomach and intestines and also makes the drugs stable so they can be stored for longer without breaking down.

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