I don’t think we’re certain at all
With Carbon, nitrogen, hydrogen and oxygen (at Earth temperature and pressure) you can form thousands of different molecules in a very stable way. They can interact predictably and intricately
The variety, size, shapes etc is mesmerising. We have seen how incredibly complex organic life is. (We simply can’t begin to replicate them non-organically)
Organic molecules can keep their structure, strength, function and stay together for thousands of years (look at fossils)
We haven’t seen the conditions on many other planets, so its possible that those conditions favour molecular stability in a different way = with different building blocks and different bonds
It’s possible that energy based lifeforms could also exist. In fact it would be preferable, in many ways
Watch K-Pax for a brilliant story and a fantastic imaginative view of an alien
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