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Sitting is not a anatomically good postion to poop in, a low squat is better. Also our diets play a big part of it, modern processed food being some of the worse, but even ‘natural foods’ are not natural to humans and we can;t break them down fully. There are other factors as well such as being bi-pedal changing our anatomical layout, our high level of cleanliness and approaches to achive it, and societal norms/requirments of civilization (like waste mangment)
Humans havn’t always wiped, and a lot of animals actually do by licking/dragging bum ect.
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