Why aren’t retrovirus enzymes (namely reverse transcriptase and integrase) being used to insert genes in our genome as a way to fight or cure certain diseases?
In: 4
In fact we do. If you know what these proteins/enzymes do (basically open, modify, cut DNA) we actually use things like this in CAR-T therapy (treating a certain type of white blood cell, T-cells, before giving them back to the patient) and in CRISPR gene editing.
https://www.ncbi.nlm.nih.gov/books/NBK19432/
Latest Answers