Why can humans build up a tolerance to some medications but not others?

Question

Edit: Thank you very much for the gold! I hope the comments made to this post were as helpful to others as they were to me.

In: Biology

Answer 1

It basically depends on how the drug works. If, for example, the drug is meant to add or adjust a chemical that is imbalanced, your body can stop producing as much of that chemical or, thinking you have enough, shut off the receptors to it. This is a reason why taking testosterone is dangerous. Your body might not produce enough of it once you stop.