why does one strand have to lag? doesn’t DNA polymerase III bind to 3′ OH ends of RNA primers and then synthesize in a 5′ to 3′ direction? don’t all the RNA primers have a 3′ end for the polymerase to bind to? so why is one strand able to synthesize continuously while the other does it bit by bit?
please help ya girl broke down while studying in Starbucks because she couldn’t understand even after way too long
In: 3
Because the 3’ OH is on the other side for the lagging strand so synthesis has to occur in the opposite direction of travel.
No matter which way you go one strand will have 3’ showing while the other will have 5’ so u cant add to both in the same direction.
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