I don’t know the science behind it but a salt water fish is evolved to live in salt water. Putting it in fresh water is like putting us on the top of Mount Everest. It’s technically air up there but it’s so different from the air we normally breathe we aren’t adapted to use it.
Salt in high amounts is toxic to most life. For life that is adapted to live in salt water a fresh water environment would be toxic to them.
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