Exertion doesn’t use just oxygen.
Your muscles and organs are not directly connected to your lungs, blod needs to carry nutrients and oxygen.
There are multiple steps between the air and your muscles, each system is either governed by physics and can’t be improved or could be improved but since they all connected and other systems pull them back and not improved in the end.
The peak physical condition is when you regulalry exert yourself, your heart is healthy and is accustomed to frequent exertion. (cardio) Your blood is healthy has enough blood cells that can transfer oxygen and nutrients. your lung is healthy and most of the inner surface is still healthy
Then you have the most amount of stamina, but that is also finite and cannot be extended after a point, without disturbing the delicate balance of the systems.
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