One of the factors is that tobacco had a tendency to absorb a natural low level radioactive isotope of naturally occurring plutonium from the soil as it grows. Smoking can put that isotope inside you over a long period of time which can compound the effect of it’s radioactivity to a level that can cellular mutation which can lead to cancer.
This is what was explained to me by an instructor I had some years back and I may be remembering parts wrong but I think I got the gist right.
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