It’s actually not a problem if you don’t have stomach problems. You’re taking two stomach irritants and that may make stomach pain worse…but so can a basket of fried jalapeños. That said, hangovers are partially from dehydration but are also significantly due to inflammation, especially hangovers from more complex distillations like older brown liquors and red wine. Taking an NSAID while still drunk/before bed can dramatically improve how you feel later.
Generally NSAIDS are very safe unless you have kidney disease and induced stomach pain will get better in a day or two or sooner with food and tums. We take them for granted but they were considered a miracle when invented. They were solid pain killers and inflammation reducers that were not narcotics, were not addictive, and were not steroids. They also reduced fever. They also were very hard to overdose on. Great stuff.
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