“The dose makes the poison,” goes the Paracelsus Maxim. This goes for non-drug compounds as vital as water & oxygen, which will engager life when too concentrated in an organism. Not all drugs are bad for the body (dose dependant, largely) or even addictive, but all create metabolic consequences. Caffeine, while addictive, seems to be ‘neuroprotective’ for cognitive health as we age. GHB & DMT are two ‘drugs’ used for intoxication which your body creates itself. While GHB has a very narrow dose:risk ratio, DMT seems very safe in very large doses. That said, too much caffeine can result in fatal overdose… My love of coffee pursues this irreversible limit each day.
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