why do drugs stay in one’s system for much longer than their effect? For example, diazepam stays in a person’s system 8-10 days, but it’s effects last 4-5 hours? Why the difference?
In: Chemistry
Simply, the drug concentration drops over time from first dose. But the therapeutic effect depends on that concentration. But statements like “stay in ones system’ usually refer to how low a concentration can still be measured. So if a drug needs to be at a concentration of say, 0.1 mg/liter of blood. but can be measured down to levels as low as 0.0000000001mg/liter. that counts as still in the system, but way,way,way too low to do any action.
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