The title says it all really. If I drink a small Red Bull with 80 mg it makes me twitchy, but a 200 mg coffee barely even affects me.
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There’s also something called situational specificity of tolerance–essentially this means that over time, your body gets used to a stimulus delivered on a particular way, such as receiving caffeine from a cup of coffee. Meanwhile, your body will react more strongly to the same amount of caffeine delivered in another, novel form, like an injection or fruity tasking drink.
It’s been a while since I studied it, but could be something similar at play?
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