It’s not exactly a “biological link” rather rodents are an animal that breeds quickly and is easy/cheap to feed. So they make excellent initial test subjects. As mammals they share most of the organs that humans have so it can be a decent way to test things.
Using primates like chimps would provide us with a closer comparison, but chimps are an expensive animal to keep. Especially if the thing you’re testing may or may not kill the subject. All that is ignoring the simple revulsion people have to animal testing on primates moreso than rodents.
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