Why do people claim ketamine will have long lasting or permanent impact on your mental health, but other NMDAR-antagonists don’t?

Question

If I take dextromethorphan (NyQuil) then four or so hours later I’m back to feeling like I did before I took it.

Just to be clear, I’m asking about taking ketamine under the supervision of a doctor. Not recreationally.

In: 23

Answer 1

It may or may not be BS, but the way i understood it is that the ketemine has a temporary side effect that makes your brain a bit more malliable(easier to change) .

I was told a weekly supervised ketemine session would be immidietly followed by a therapy session. The ketemine is supposed to make it easier to permanently change how your brain processes input in a more healthy way, by not taking nearly as many repetitions to rewrite old pathways.

So the effects of the drug is temporary, but any changes you make to your brain while under the effects of the drug may be longer lasting.