Worth keeping in mind that we live in a different world, and our bodies reflect it. A study was done recently that found that the Black Death selected for resistant humans, but that resistance likely came with mutations for autoimmune diseases.
Our bodies used to be riddled with parasites and exposed to lots more bacteria than now. Diets also had more wild plants, and a higher tolerance for bitter foods, both likely giving us plant compounds we no longer get. Our food was less clean, so we were also ingesting bread with more insect parts in it. This is all to say that our bodies evolved with very different inputs in mind than our highly processed cleaner foods.
We also know that ancient people suffered from a variety of chronic stomach issues, so we can’t even be sure this is a new thing.
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