Spiders, like all non-human organisms, are simply biological robots programmed by natural selection. They do not and cannot engage in reasoning, so it takes, in many cases, thousands of generations to reprogram them to respond differently than they already naturally do. But their programming is empirically successful, so spiders don’t run away as soon as they see a human because doing so would not be an adaptive behavior; they are more likely to pass on their genes by ignoring our presence than they are to do so by fleeing it. The relative difference in size might cause you to believe this is unintuitive because of the ease with which we can kill them when we want to, but it actually works the other way: they are more likely to see us than we are to see them, so even if every human unerringly killed every spider they notice, it is unlikely to make fleeing our presence an adaptive behavior.
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