First of all, Oxygen, you can’t run at your max speed forever because you’re burning through oxygen faster than you can breathe if you run at max speed for too long, you’re basically suffocating yourself. This would be what most people refer to as “Getting tired” when they run 100m at full speed and struggle to breathe afterward.
Second, Cellular Fermentation, Your body doesn’t just rely on oxygen to burn sugar for energy, your cell will perform “Fermentation” if it can’t get enough oxygen. Fermentation is a process to turn sugar into energy without oxygen but it produces Lactic acid. Lactic acid isn’t very harmful but too much of it will damage your tissue causing muscle fatigue.
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