There are several reasons. For some meds taking it all at one time would make you sick. Even like Tylenol. If you took 8 extra strength at one time it could damage your liver. Taking them 2 at a time separated by 6 hours makes it safe.
Also, your body metabolizes them at different rates. Using Tylenol again, after 6 hours it’s pretty much out of your system. So if you don’t take it every 6 hours you won’t get the relief you seek.
Some meds metabolizes slower in your body so you only need to take them once a day.
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