As the question says, why do we need to refrigerate something after it’s opened? I have a bottle of Chipotle Sauce I got from Target, and it was happily sitting in the shelves for who knows how long unrefrigerated. It says on the label to refrigerate after opening. Why? And I don’t think it’s because Target is air conditioned. Some bodegas in nyc for example are un air-conditioned and will sell similar stuff.