In school we learned ” what you save in energy, you have to increase the way.” By that rule you should use the exact same amount of energy (fuel) for the same distance no matter what speed. I’ve asked a few people, but no-one could give me a good answer.
Engines are designed to have an efficiency “sweet spot,” I believe around 55 mph.
Also, drag from the air is not linear with speed. If you double your speed, you more than double the air resistance. The same is also probably true for other friction losses.
Latest Answers