why does a dissolvable medication work better when dissolved, but not swallowed?


I take hyoscyamine (an anti-spasmodic used for IBS), which no matter the manufacturer is directed to be dissolved under the tongue, not swallowed. Why does it work best when dissolved?

In: 1

1 – It is absorbed faster through the gums than it is through the stomach lining.

2 – Stomach acid. The medication might not take kindly to stomach acid.

Most hyoscyamine can be taken orally too, not just sub-lingual (dissolved under the tongue) without diminishing it’s efficacy. Your doctor may think that the medicine is more tolerable for patients if dissolved, so that’s the prescription you’re getting. It really shouldn’t matter generally, but you may have other issues your doctor is concerned about. Could also be that’s just what they’re used to, and since it works, they just keep going with it. There are versions that can be swallowed and you should ask your doctor about it if that’s a concern.

Under the tongue the medication is going straight in to the blood stream via the thin skin in your mouth, if you swallow it there’s a whole lot of other things involved before it gets in to your blood… if it even can without being destroyed.