Sparing the details, a colleague of mine recently had his big toe amputated due to diabetes. I wondered why being diabetic could lead to this as it’s common.
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I did my PhD on diabetic neuropathy.
The elevated sugar level damages nerves, starting with the longest ones first; those in your feet and hands.
The needles & pins sensation diabetics experience is their nerves whithering and dying.
As the nerves decay they impact the immune system so any cuts/lesions are slow to heal & this can cause gangrene.
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