Diabetes affect blood circulation in your whole body. Usually the first thing people will notice is their feet since it is the farthest point from the heart.
You begin losing sensation, then any injuries will take a long time to heal up to a point where no blood will reach the foot and will need to be amputated. There are procedures to help with this, but it usually only delay the inevitable.
Apart from the feet, usually people with diabetes will have kidney problems and will often necessitate dyalisis.
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